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Alchemy is the art and science of mixing reagents in order to obtain transformations of their qualities and effects. In '''Noita''', the great majority of alchemical reagents are in liquid form, preserved in flasks. They can be mixed with other liquids or solid materials to produce a different substances entirely. It would take a patient alchemist with access to all kinds of elements to discover how many unique concoctions exist...
+
Alchemy is the art and science of mixing reagents in order to obtain transformations of their qualities and effects. In '''Noita''', the great majority of alchemical reagents are in liquid form, preserved in flasks. They can be mixed with other liquids or solid materials to produce different substances entirely. It would take a patient alchemist with access to all kinds of elements to discover how many unique concoctions exist...
   
 
== General Introduction ==
 
== General Introduction ==
Line 15: Line 15:
 
== Known Recipes ==
 
== Known Recipes ==
 
* List is sorted into base ingredients and catalysts (though in some cases these are interchangeable).
 
* List is sorted into base ingredients and catalysts (though in some cases these are interchangeable).
* Ingredients marked with * are not consumed by the process and will remain with the resulting product.
+
* Ingredients marked with <code>*</code> are not consumed by the process and will remain with the resulting product.
 
{| class="wikitable sortable" style="text-align:center"
 
{| class="wikitable sortable" style="text-align:center"
  +
! Result
 
! Primary ingredient (base)
 
! Primary ingredient (base)
 
!Secondary ingredients (catalysts)
 
!Secondary ingredients (catalysts)
! Result
 
 
! Notes
 
! Notes
 
|-
 
|-
|[[Toxic Sludge]]
+
![[(evaporates)]]
|[[Water]]*
+
|[[Acid]]
|[[Water]]
+
|[[Teleportatium]]
  +
|A small amount of teleportatium evaporated a large volume of acid, in Dec 1 2020 16:53:10 build.
|Use this to create large volumes of water from pools of sludge.
 
 
|-
 
|-
  +
![[Alchemic precursor|Alchemic Precursor]]
|[[Toxic Sludge]]
 
  +
|?
|[[Mud]]*
 
  +
|?
|[[Swamp]]
 
  +
|Three ingredients are randomly generated on each seed. (see [[#Lively Concoction and Alchemic Precursor|#more info below]])
|This can be a substitute for water, but peat grows on top which does not behave similarly to water.
 
 
|-
 
|-
|[[Toxic Sludge]]
+
![[Ambrosia]]
|[[Swamp]]*
+
(+ [[Poison]])
|[[Swamp]]
+
|[[Honey]]
  +
|[[Diamond]]
|This can be used to create large volumes of swamp from pools of sludge.
 
  +
|
 
|-
 
|-
|[[Slime]]
+
![[Berserkium]]
|[[Water]]*
+
|[[Whiskey]]
  +
|Frog Meat (corpse of a [[Konna]] / [[Jättikonna]])*
|Slime Mist
 
 
|
 
|
 
|-
 
|-
|[[Slime]]
+
![[Brass]]
|[[Whiskey]]*
+
(+ [[Smoke]])
|[[Smoke]]
+
|[[Copper]]
  +
|[[Teleportatium]]
  +
|
 
|
 
|
 
|-
 
|-
  +
![[Chaotic Polymorphine]]
|[[Invisiblium]]
 
|[[Water]]*
+
|[[Polymorphine]]
|[[Water]]
+
|[[Toxic Sludge]]*
  +
|
|Making water doubly dangerous to players using Invisiblium.
 
  +
|
  +
|-
  +
![[Chaotic Polymorphine]]
  +
|[[Toxic Sludge]]
  +
|[[Polymorphine]]*
  +
|
  +
|
 
|-
 
|-
  +
![[Concentrated Mana]]
 
|[[Water]]
 
|[[Water]]
 
|[[Concentrated Mana]]*
 
|[[Concentrated Mana]]*
|[[Concentrated Mana]]
 
 
|Because, Water + Toxic Sludge = More Water. You can do
 
|Because, Water + Toxic Sludge = More Water. You can do
   
 
Toxic Sludge to Water then Water to Concentrated Mana.
 
Toxic Sludge to Water then Water to Concentrated Mana.
  +
|
 
|-
 
|-
  +
![[Copper]]
|Any metal
 
  +
(+ [[Smoke]])
  +
|[[Silver]]
  +
|[[Polymorphine]]
  +
|
  +
|-
  +
![[Diamond]]
  +
(+ [[Smoke]])
  +
|[[Silver]] + [[Copper]]
  +
|[[Blood]]
  +
|
  +
|-
  +
![[Draught of Midas]]
  +
|[[Alchemic precursor|Alchemic Precursor]]
  +
|[[Meat]]
  +
|
  +
|
  +
|-
  +
![[Freezing Vapour]]
  +
|[[Teleportatium]] / [[Unstable Teleportatium]]
  +
|[[Fire]]
  +
|
  +
|
  +
|-
  +
![[Fire]]
  +
|[[Teleportatium]] / [[Unstable Teleportatium]]
 
|[[Concentrated Mana]]*
 
|[[Concentrated Mana]]*
  +
|The fire will burn parts of the Teleportatium into [[Freezing Vapour]].
|[[Steam]]
 
  +
|
|Useful in the later biomes where steel is more present.
 
 
Be careful, as this also applies to both powder [[gold]] and gold nuggets.
 
 
|-
 
|-
|[[Acceleratium]]
+
![[Flummoxium]]
|[[Levitatium]]
+
|[[Worm Pheromone]]
|[[Hastium]]
+
|[[Worm Blood]]
  +
|
|Gives you both potion effects, but at half the duration per drink.
 
  +
|
 
|-
 
|-
|[[Polymorphine]]
+
![[Fools Gold]]
|[[Toxic Sludge]]*
+
|[[Urine]]
  +
|[[Lava]]
|[[Chaotic Polymorphine]]
 
  +
|
 
|
 
|
 
|-
 
|-
  +
![[Guiding Powder]]
  +
|[[Unstable Teleportatium]]
 
|[[Flummoxium]]
 
|[[Flummoxium]]
|[[Oil]] and [[Blood]]
 
|[[Unstable Polymorphine]]
 
 
|
 
|
 
|-
 
|-
  +
![[Gunpowder]] (active)
 
|[[Acceleratium]] / [[Levitatium]] / [[Hastium]]
 
|[[Acceleratium]] / [[Levitatium]] / [[Hastium]]
 
|[[Slime]]
 
|[[Slime]]
|[[Gunpowder]] (active)
 
 
|This can and will kill you if you get damaged while standing in a pool of potion with the Slime Blood Perk
 
|This can and will kill you if you get damaged while standing in a pool of potion with the Slime Blood Perk
  +
|
 
|-
 
|-
  +
![[Gunpowder]] (active)
|[[Whiskey]]
 
  +
|[[Healthium]] / [[Lively concoction|Lively Concoction]]
|Frog Meat ([[Konna]] / [[Jättikonna]] corpse)*
 
|[[Berserkium]]
+
|[[Purifying Powder]]
  +
|
 
|
 
|
 
|-
 
|-
  +
![[Hastium]]
  +
|[[Acceleratium]]
  +
|[[Levitatium]]
  +
|Gives you both potion effects, but at half the duration per drink.
  +
|
  +
|-
  +
![[Levitatium]]
  +
|Metal Powder ([[Gold]]/ [[Copper]]/ [[Brass]]/ [[Silver]]) or [[Diamond]]
 
|[[Flummoxium]]
 
|[[Flummoxium]]
  +
|
|[[Berserkium]]
 
|[[Pheromone]]
 
 
|
 
|
 
|-
 
|-
  +
![[Lively concoction|Lively Concoction]]
|[[Worm Pheromone]]
 
  +
|?
|[[Worm Blood]]
 
  +
|?
  +
|Three ingredients are randomly generated on each seed. (see [[#Lively Concoction and Alchemic Precursor|#more info below]])
  +
|
  +
|-
  +
![[Metal Dust]]
  +
(+ [[Smoke]])
  +
|[[Brass]]
  +
|[[Unstable Teleportatium]]
  +
|
  +
|-
  +
![[Mysterious Fungus]]
  +
|Fungus Blood(evaporates quickly)
  +
|[[Toxic Sludge]] and Sand
  +
|
  +
|
  +
|-
  +
![[Mysterious Fungus]]
  +
|[[Mysterious Fungus]]
  +
|[[Toxic Sludge]] or Sand
  +
|
  +
|
  +
|-
  +
!Peat
  +
|[[Swamp]]
  +
|[[Toxic Sludge]]
  +
|
  +
|
  +
|-
  +
![[Pheromone]]
 
|[[Flummoxium]]
 
|[[Flummoxium]]
  +
|[[Berserkium]]
  +
|
 
|
 
|
 
|-
 
|-
|[[Freezing Liquid]]
+
![[Purifying Powder]]
|[[Worm Blood]]*
+
|[[Brass]]
  +
|[[Diamond]]
  +
|
  +
|
  +
|-
  +
![[Purifying Powder]]
  +
(+ [[Smoke]])
  +
|[[Diamond]] + [[Silver]]
 
|[[Worm Blood]]
 
|[[Worm Blood]]
 
|
 
|
 
|-
 
|-
  +
![[Meat|Rotten Meat]]
|Metal Powder ([[Gold]]/ [[Copper]]/ [[Brass]]) or [[Diamond]]
 
|[[Flummoxium]]
+
|[[Meat]]
  +
|[[Poison (Material)|Poison]]
|[[Levitatium]]
 
 
|
 
|
 
|-
 
|-
  +
!Salt
|[[Teleportatium]] / [[Unstable Teleportatium]]
 
|[[Concentrated Mana]]*
+
|[[Brine]]
 
|[[Fire]]
 
|[[Fire]]
  +
|
|The fire will burn parts of the Teleportatium into [[Freezing Vapour]].
 
|-
 
|[[Teleportatium]]
 
|[[Whiskey]]*
 
|[[Unstable Teleportatium]]
 
 
|
 
|
 
|-
 
|-
|[[Teleportatium]]
+
![[Shock Powder]]
  +
|[[Brass]]
|[[Unstable Teleportatium]]*
 
|[[Unstable Teleportatium]]
+
|[[Liquid Fire]]
 
|
 
|
 
|-
 
|-
  +
![[Slime Mist]]
|[[Unstable Teleportatium]]
 
 
|[[Slime]]
 
|[[Slime]]
|[[Teleportatium]]
+
|[[Water]]*
  +
|
|Unstable Teleportan=tium will quickly convert the newly created normal Teleportatium back into Unstable unless only very small quantities of Unstable are used.
 
  +
|
 
|-
 
|-
|[[Honey]]
+
![[Silver]]
  +
(+ [[Smoke]])
 
|[[Diamond]]
 
|[[Diamond]]
|[[Ambrosia]] + [[Poison]]
+
|[[Chaotic Polymorphine]]
 
|
 
|
 
|-
 
|-
|[[Brass]]
+
![[Silver]]
|[[Diamond]]
+
(+ [[Smoke]])
  +
|[[Gold]] (Powder)
|[[Purifying Powder]]
 
  +
|[[Chaotic Polymorphine]]
 
|
 
|
 
|-
 
|-
  +
![[Silver]]
|Most liquids
 
  +
(+ [[Smoke]])
|[[Purifying Powder]]*
 
  +
|[[Copper]] + [[Brass]]
 
|[[Water]]
 
|[[Water]]
 
|
 
|
 
|-
 
|-
  +
![[Slime]]
|[[Healthium]] / [[Lively concoction|Lively Concoction]]
 
  +
(+ [[Smoke]])
|[[Purifying Powder]]
 
|[[Gunpowder]] (active)
+
|[[Blood]]
  +
|[[Poison (Material)|Poison]]
 
|
 
|
 
|-
 
|-
  +
!Slime Mist
|Fungus
 
  +
|[[Slime]]
|[[Toxic Sludge]] and Sand
 
|[[Mysterious Fungus]]
+
|[[Fire]]
  +
|
|Will turn Sand and Toxic Sludge into itself on contact.
 
 
|-
 
|-
  +
![[Smoke]]
  +
|[[Slime]]
  +
|[[Whiskey]]*
  +
|
  +
|
  +
|-
  +
![[Smoke]]
  +
|[[Cement]]
  +
|[[Lava]]
  +
|Both solid and liquid forms of cement will react.
  +
|
  +
|-
  +
![[Smoke]]
  +
|Peat
  +
|[[Lava]]
  +
|
  +
|
  +
|-
  +
![[Steam]]
  +
|Any metal
  +
|[[Concentrated Mana]]*
  +
|Useful in the later biomes where steel is more present.
  +
  +
Be careful, as this also applies to both powder [[gold]] and gold nuggets.
  +
|
  +
|-
  +
![[Swamp]]
  +
|[[Toxic Sludge]]
  +
|[[Mud]]*
  +
|This can be a substitute for water, but peat grows on top which does not behave similarly to water.
  +
|
  +
|-
  +
![[Swamp]]
  +
|[[Toxic Sludge]]
  +
|[[Swamp]]*
  +
|This can be used to create large volumes of swamp from pools of sludge.
  +
|
  +
|-
  +
![[Teleportatium]]
  +
|[[Unstable Teleportatium]]
  +
|[[Slime]]
  +
|Unstable Teleportatium will quickly convert the newly created normal Teleportatium back into Unstable unless only very small quantities of Unstable are used.
  +
|
  +
|-
  +
![[Teleportatium]]
  +
|[[Water]]
  +
|[[Wizards' Den|Wizard stone]]
  +
|
  +
|-
  +
![[Unstable Polymorphine]]
  +
|[[Flummoxium]]
  +
|[[Oil]] and [[Blood]]
  +
|
  +
|
  +
|-
  +
![[Unstable Teleportatium]]
  +
|[[Teleportatium]]
  +
|[[Whiskey]]*
  +
|
  +
|
  +
|-
  +
![[Unstable Teleportatium]]
  +
|[[Teleportatium]]
  +
|[[Unstable Teleportatium]]*
  +
|
  +
|
  +
|-
  +
![[Void Liquid]]
 
|[[Toxic Sludge]]
 
|[[Toxic Sludge]]
 
|[[Worm Blood]] and Fungus Powder
 
|[[Worm Blood]] and Fungus Powder
  +
|
|[[Void Liquid]]
 
 
|
 
|
 
|-
 
|-
  +
![[Void Liquid]]
|?
 
  +
|[[Diamond]]
|? + ?
 
  +
|[[Chaotic Polymorphine]]+ [[Toxic Sludge]]
|[[Lively concoction|Lively Concoction]]
 
  +
|
|Ingredients are randomly generated on each seed.
 
 
|-
 
|-
  +
![[Water]]
|?
 
  +
|[[Impure|"Impure"]]
|? + ?
 
  +
|[[Purifying Powder]]*
|[[Alchemic precursor|Alchemic Precursor]]
 
  +
|
|Ingredients are randomly generated on each seed.
 
  +
|
 
|-
 
|-
  +
![[Water]]
|[[Alchemic precursor|Alchemic Precursor]]
 
|[[Meat]]
+
|[[Invisiblium]]
|[[Draught of Midas]]
+
|[[Water]]*
  +
|Making water doubly dangerous to players using Invisiblium.
 
|
 
|
 
|-
 
|-
|[[Cement]]
+
![[Water]]
|[[Lava]]
+
|[[Toxic Sludge]]
|[[Smoke]]
+
|[[Water]]*
  +
|Use this to create large volumes of water from pools of sludge.
|Both solid and liquid forms of cement will react.
 
  +
|
  +
|-
  +
![[Worm Blood]]
  +
|[[Freezing Liquid]]
  +
|[[Worm Blood]]*
  +
|
  +
|
 
|}
 
|}
   
 
There are many other less-useful interactions which follow from basic physical principles:
 
There are many other less-useful interactions which follow from basic physical principles:
   
* [[Water]] + [[Fire]] = [[Steam]]
+
*[[Steam]] = [[Water]] + [[Fire]]
* [[Water]] + [[Lava]] = [[Rock]]
+
*Ice = [[Water]] + [[Freezing Liquid]]
* [[Slime]] + [[Fire]] = [[Slime]] Mist
+
*[[Rock]] = [[Water]] + [[Lava]]
* [[Freezing Liquid]] + [[Lava]] = [[Dense Rock]]
+
*Dense Rock = [[Freezing Liquid]] + [[Lava]]
* [[Toxic Sludge]] + [[Lava]] = [[Toxic Rock]] (causes damage on contact)
+
*[[Toxic Rock]] (causes damage on contact) = [[Toxic Sludge]] + [[Lava]]
*[[Poison]] + [[Lava]] = [[Poisonous Rock]] (similar to Toxic Rock)
+
*Poisonous Rock (similar to Toxic Rock) = [[Poison]] + [[Lava]]
* [[Blood]] + [[Lava]] = [[Volcanic Rock]]
+
*Volcanic Rock = [[Blood]] + [[Lava]]
* [[Urine]] + [[Lava]] = [[Fools Gold]]
+
*Ground = [[Mud]] + [[Lava]]
* [[Mud]] + [[Lava]] = [[Ground]]
+
*[[Glowing Matter]] = [[Brine]] + [[Lava]]
* [[Brine]] + [[Lava]] = [[Glowing Matter]]
 
* [[Brine]] + [[Fire]] = [[Salt]]
 
* [[Teleportatium]] / [[Unstable Teleportatium]] + [[Fire]] = [[Freezing Vapour]]
 
   
More interactions are detailed on the [https://docs.google.com/spreadsheets/d/1K7SXZTyvhUYMyl4xVwvbxLqGoUJJUQUHav7_PaCrrb0/edit?usp=sharing Liquid Interaction Chart]
+
More interactions are detailed on the [https://docs.google.com/spreadsheets/d/1K7SXZTyvhUYMyl4xVwvbxLqGoUJJUQUHav7_PaCrrb0/edit?usp=sharing Liquid Interaction Chart]<sup>(outdated)</sup> and the [https://docs.google.com/spreadsheets/d/1MVcKCzQ9-LL6JNh1sle36MNrKLXsgDdAyKw39NxVl-Q/edit?usp=sharing 1.0 Material Interactions & Data Sheet].
   
 
== Lively Concoction and Alchemic Precursor ==
 
== Lively Concoction and Alchemic Precursor ==
These two concoctions have their recipes [[Random Materials|randomly generated]] at the start of each new game. The recipes are always in the ternary form, being composed of three reagents. [[Lively concoction|Lively Concoction]] is a most sought draught who heals at a better rate than the also very rare [[Healthium]] potion. The [[Alchemic precursor|Alchemic Precursor]] is probably a hint into more complex recipes which this is a indispensable reagent.
 
   
  +
These two concoctions have their recipes [[Random Materials|randomly generated]] at the start of each new game. The recipes are always in the ternary form (requiring three reagents).
A working web-based recipe calculator for [[Lively concoction|Lively Concoction]] and [[Alchemic precursor|Alchemic Precursor]] can be found here: [https://neffc.github.io/narg/ neffc.github.io/narg/]
 
  +
  +
[[File:Lively_Concotion_Flask.png|20px]] [[Lively Concoction]] is an extremely useful healing potion, that heals at a better rate than the (also very rare) [[Healthium]] potion.
  +
  +
[[File:Alchemic_precursor_flask.png|20px]] [[Alchemic Precursor]] is an indispensable reagent for creating the elusive [[Draught of Midas]].
  +
  +
Finding the ingredients for each concoction is unpredictable, and an experienced player will keep a close watch for their distinct colours appearing.
   
  +
<small>(There are ways to cheat to find the recipe via a [https://neffc.github.io/narg/ calculator website] by Neff, or an [https://modworkshop.net/mod/29782 in-game mod] by cjneff.)</small>
You can also download a mod that displays the recipes while in game by cjneff which can be found here: https://modworkshop.net/mod/29782. Though as of right now [https://steamcommunity.com/sharedfiles/filedetails/?id=1984977713&searchtext=Cheatgui Cheatgui] a popular tool amongst the community for testing things inside the game that is hard to achieve in normal play. Cheatgui's widgets for recipe display for [[Lively concoction|Lively Concoction]] and [[Alchemic precursor|Alchemic Precursor]] are not up to date with modern seed calculation meaning they still do not work.
 
   
 
== Trivia ==
 
== Trivia ==
   
*[[Draught of Midas]] is a reference to king Midas, a man who supposedly gained the ability to convert everything he touched into [[gold]].
+
* [[Draught of Midas]] is a reference to king Midas, a man who, in a greek myth, gained the ability to convert everything he touched into [[Gold]].
*[[Draught of Midas]] and [[Lively concoction|Lively Concoction]] are both most likely references to transmutation and the panacea respectively, both known to be the ultimate works of Alchemy.
+
* [[Draught of Midas]] and [[Lively Concoction]] are both most likely references to transmutation and the panacea respectively, both known to be the ultimate works of Alchemy in hermetic texts.
*The [[Temple of the Art|Temple of The Art]] is most likely a nod to "The Arts" which is a another name for the hermetic practices.
 
*[[Void Liquid|Void liquid]] is the densest matter in game
 

Revision as of 14:35, 20 October 2021

Alchemy is the art and science of mixing reagents in order to obtain transformations of their qualities and effects. In Noita, the great majority of alchemical reagents are in liquid form, preserved in flasks. They can be mixed with other liquids or solid materials to produce different substances entirely. It would take a patient alchemist with access to all kinds of elements to discover how many unique concoctions exist...

General Introduction

In a world where every pixel is simulated, Alchemy occupies a main role with no surprises. Even if the player chooses to avoid picking up potions and focuses in wand-building, they must be aware of the many reactions that endlessly occur in the world of Noita. Explosions, corrosions and fires share space with purifications, teletransportations, charmings and metamorphic effects, making alchemical knowledge essential to survival.

Also, the world will spawn many sorts of materials that can react to each other in some way, while having their own particularities while isolated in puddles, mounds or tanks. So, the majority of reactions that occur while delving into the mysteries of Noita will not be caused by the player's direct actions at all. With this in mind, the character starts with three forms of modifying their surroundings:

  • A wand that shoots low-damage projectiles like Spark Bolt, Energy Sphere or Spitter Bolt, some of which can reduce powders and silence small flames at a very slow rate.
  • A wand with explosive spells such as Bomb, Firebolt or Magic Missile, which can remove chunks of terrain and/or ignite flammable materials.
  • A potion that changes its contents every game with the possibility of containing something helpful to the player or something harmful to creatures.

Additional potions can be found atop magical pedestals while exploring the dungeon, encouraging the player to make mixtures and try new reactions.

Known Recipes

  • List is sorted into base ingredients and catalysts (though in some cases these are interchangeable).
  • Ingredients marked with * are not consumed by the process and will remain with the resulting product.
Result Primary ingredient (base) Secondary ingredients (catalysts) Notes
(evaporates) Acid Teleportatium A small amount of teleportatium evaporated a large volume of acid, in Dec 1 2020 16:53:10 build.
Alchemic Precursor ? ? Three ingredients are randomly generated on each seed. (see #more info below)
Ambrosia

(+ Poison)

Honey Diamond
Berserkium Whiskey Frog Meat (corpse of a Konna / Jättikonna)*
Brass

(+ Smoke)

Copper Teleportatium
Chaotic Polymorphine Polymorphine Toxic Sludge*
Chaotic Polymorphine Toxic Sludge Polymorphine*
Concentrated Mana Water Concentrated Mana* Because, Water + Toxic Sludge = More Water. You can do

Toxic Sludge to Water then Water to Concentrated Mana.

Copper

(+ Smoke)

Silver Polymorphine
Diamond

(+ Smoke)

Silver + Copper Blood
Draught of Midas Alchemic Precursor Meat
Freezing Vapour Teleportatium / Unstable Teleportatium Fire
Fire Teleportatium / Unstable Teleportatium Concentrated Mana* The fire will burn parts of the Teleportatium into Freezing Vapour.
Flummoxium Worm Pheromone Worm Blood
Fools Gold Urine Lava
Guiding Powder Unstable Teleportatium Flummoxium
Gunpowder (active) Acceleratium / Levitatium / Hastium Slime This can and will kill you if you get damaged while standing in a pool of potion with the Slime Blood Perk
Gunpowder (active) Healthium / Lively Concoction Purifying Powder
Hastium Acceleratium Levitatium Gives you both potion effects, but at half the duration per drink.
Levitatium Metal Powder (Gold/ Copper/ Brass/ Silver) or Diamond Flummoxium
Lively Concoction ? ? Three ingredients are randomly generated on each seed. (see #more info below)
Metal Dust

(+ Smoke)

Brass Unstable Teleportatium
Mysterious Fungus Fungus Blood(evaporates quickly) Toxic Sludge and Sand
Mysterious Fungus Mysterious Fungus Toxic Sludge or Sand
Peat Swamp Toxic Sludge
Pheromone Flummoxium Berserkium
Purifying Powder Brass Diamond
Purifying Powder

(+ Smoke)

Diamond + Silver Worm Blood
Rotten Meat Meat Poison
Salt Brine Fire
Shock Powder Brass Liquid Fire
Slime Mist Slime Water*
Silver

(+ Smoke)

Diamond Chaotic Polymorphine
Silver

(+ Smoke)

Gold (Powder) Chaotic Polymorphine
Silver

(+ Smoke)

Copper + Brass Water
Slime

(+ Smoke)

Blood Poison
Slime Mist Slime Fire
Smoke Slime Whiskey*
Smoke Cement Lava Both solid and liquid forms of cement will react.
Smoke Peat Lava
Steam Any metal Concentrated Mana* Useful in the later biomes where steel is more present.

Be careful, as this also applies to both powder gold and gold nuggets.

Swamp Toxic Sludge Mud* This can be a substitute for water, but peat grows on top which does not behave similarly to water.
Swamp Toxic Sludge Swamp* This can be used to create large volumes of swamp from pools of sludge.
Teleportatium Unstable Teleportatium Slime Unstable Teleportatium will quickly convert the newly created normal Teleportatium back into Unstable unless only very small quantities of Unstable are used.
Teleportatium Water Wizard stone
Unstable Polymorphine Flummoxium Oil and Blood
Unstable Teleportatium Teleportatium Whiskey*
Unstable Teleportatium Teleportatium Unstable Teleportatium*
Void Liquid Toxic Sludge Worm Blood and Fungus Powder
Void Liquid Diamond Chaotic Polymorphine+ Toxic Sludge
Water "Impure" Purifying Powder*
Water Invisiblium Water* Making water doubly dangerous to players using Invisiblium.
Water Toxic Sludge Water* Use this to create large volumes of water from pools of sludge.
Worm Blood Freezing Liquid Worm Blood*

There are many other less-useful interactions which follow from basic physical principles:

More interactions are detailed on the Liquid Interaction Chart(outdated) and the 1.0 Material Interactions & Data Sheet.

Lively Concoction and Alchemic Precursor

These two concoctions have their recipes randomly generated at the start of each new game. The recipes are always in the ternary form (requiring three reagents).

Lively Concotion Flask Lively Concoction is an extremely useful healing potion, that heals at a better rate than the (also very rare) Healthium potion.

Alchemic precursor flask Alchemic Precursor is an indispensable reagent for creating the elusive Draught of Midas.

Finding the ingredients for each concoction is unpredictable, and an experienced player will keep a close watch for their distinct colours appearing.

(There are ways to cheat to find the recipe via a calculator website by Neff, or an in-game mod by cjneff.)

Trivia

  • Draught of Midas is a reference to king Midas, a man who, in a greek myth, gained the ability to convert everything he touched into Gold.
  • Draught of Midas and Lively Concoction are both most likely references to transmutation and the panacea respectively, both known to be the ultimate works of Alchemy in hermetic texts.